Objective Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is an inherited adrenal steroid synthesis ...

Background and objective Cardiorespiratory polygraphy (CRP) is the predominant technology used to diagnose obstructive sleep apnoea (OSA) in tertiary centres in the UK. Nocturnal pulse oximetry (NPO) ...

Our aim was to develop guidance for general paediatricians and primary care physicians in diagnosing and managing cow’s milk protein allergy in infants. The guidelines were developed by discussion ...

Aim There is an increased use of Hormonal Contraceptives (HCs) in female adolescents, during a period of growth, development and hormonal changes.1 2 Due to the limited long-term safety data available ...

Objectives Multiplex gastrointestinal PCR (GI-PCR) allows fast and simultaneous detection of 22 enteric pathogens (including Campylobacter, Salmonella , Shigella /enteroinvasive Escherichia coli (EIEC ...

Background Most guidelines recommend the use of capillary refill time (CRT) as part of the routine assessment of unwell children, but there is little consensus on the optimum method of measurement and ...

Aims: To investigate whether weight category (underweight, average weight, overweight, and obese) at age 7.5 predicts bullying involvement at 8.5 years. Models were tested separately for boys and ...

AIM To determine the incidence of hypocalcaemia in critically ill children with meningococcal disease. METHODS In a prospective cohort study, 70 of 80 patients admitted consecutively with a clinical ...

Objective The aim was to compare quality of life (QoL) among children and adolescents with different stages of chronic kidney disease (CKD) and determine factors associated with changes in QoL. Design ...

Aims Up to 2% of all pregnancies are conceived by in vitro fertilisation (IVF) in the UK. IVF methodologies include fresh and frozen-thawed embryo transfer. Neonates conceived by frozen-thawed IVF are ...

Introduction With approximately 50% of the drugs being prescribed off-label, the pediatric population is in need for an innovative approach to establish harmonized, best evidence-based dosing ...

Background NICE has produced recent guidelines for the management of Cerebral Palsy in the under 25 s. It recommends every ‘child or young person and their parents or carers [should be] provided with ...