In addition to Bob Odenkirk, Nobody 2 returns many cast members from the first movie, including Connie Nielsen, RZA, Colin Salmon, Gage Munroe, Paisley Cadorath and Christopher Lloyd. New to the cast are John Ortiz, Colin Hanks and Sharon Stone in villainous roles.

Timo Tjahjanto takes over directing duties for this follow-up to 2021's surprise action hit about an ordinary family man who's actually a professional assassin.