As the attacks escalate, with fatalities and injuries reported on both sides, Israel issued the stark warning to Iran.

U.S. stocks opened sharply lower and oil prices jumped after Israel launched airstrikes against Iran. Israel’s defense minister Israel Katz declared a special state of emergency following the attack.

Israel and Iran opened a new chapter in their long history of conflict when Israel launched a major attack with strikes early Friday that set off explosions in the Iranian capital of Tehran. Israel said it targeted nuclear and military facilities,